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本帖最后由 邓文龙 于 2023-8-10 09:30 编辑
提高呼吸道温度(以及体温),对预防和治疗新冠病毒肺炎十分重要
我们地球上最聪明的灵长类动物人类大约自2亿前起,从像鱼那样的在水中生存的变温的脊椎动物,逐步上岸到陆地上,主要因快速运动等物理学上的需要,以及化学反应和新陈代谢快速并衡定等化学上的需要,而自然适应进化成大约摄氏37度恒温的哺乳纲动物。而像人民军队那样担负吞噬消灭新冠病毒,细菌等,防御杀敌等任务的白细胞(有白血球,淋巴细胞,单核细胞(进入鼻咽气管肺等组织中后就是重兵,大名鼎鼎的巨噬细胞)等),还有从鼻咽气管到肺为止内表面是一层起墙壁等作用抵挡新冠病毒,细菌等的侵略者,单层的上皮细胞,也是经历约2亿的自然进化出了,同样大约在摄氏37度左右担负起人类等生命至关重要的防御作用。但是在深秋季冬季初春季(如2019年12月到2020年3月,从亚洲到欧洲到北美洲等),或夏季开足冷气机,约摄氏29-23度或更低时时(亚洲到欧洲到北美洲等北半球,家庭公司车间商场等室内,汽车内电车内地铁内飞机内等),人类呼吸道温度大约在下降到摄氏34度以下时,如32度,30度,28度,乃至26度等时或更低,白细胞上皮细胞等防御作用逐步下降,直至消失。麻痹了,失效了!新冠病毒,细菌等如入无防御的呼吸道等,如入无人之境,长驱直入。在麻痹的无设防的人类呼吸道鼻咽大小气管等中,新冠病毒侵略攻入这些呼吸道上皮细胞等防御细胞只需要短短的10分钟时间,然后经过约10个小时,每个上皮细胞等生产出第一批病毒约1000个,释放出来,然后继续较低温就会出现爆发式病毒生产,那就又过10小时,第二批病毒数约1000乘1000,即20小时后变成100万个。再又过10小时,第三批病毒数约1000乘1000乘1000,即30小时后变成10亿个新冠病毒,以后更多!新冠病毒肺炎病人出现了!所以,人类呼吸道温度高等的情况,基本上是不会得新冠病毒肺炎的!提温保暖重要!(22-4-5晚11点初稿,草案)
https://www.facebook.com/hantao.gu.75/posts/514491340279597
https://www.facebook.com/hantao.gu.75
(Google English translation: )
Raising respiratory temperature (and body temperature) is important for preventing and treating COVID-19
Human beings, the smartest primate on our planet, have gradually come ashore from a variable-temperature vertebrate living in water like a fish since about 200 million years ago, mainly due to physical needs such as rapid movement, and Chemical reactions and metabolism are fast and balanced with other chemical needs, and natural adaptations evolved into mammals with a constant temperature of about 37 degrees Celsius. And white blood cells (leukocytes, lymphocytes, monocytes) that are responsible for phagocytosing and destroying new coronaviruses, bacteria, etc., and defending and killing enemies, like the People's Army (including leukocytes, lymphocytes, monocytes (after entering nasopharyngeal, tracheal, lung and other tissues are heavy soldiers, the famous macrophages)) etc.), and from the nasopharyngeal trachea to the lungs, the inner surface is a layer that acts as a wall to resist the aggressors such as the new coronavirus and bacteria. At around 37 degrees Celsius, it plays a vital role in defense of life such as human beings. But in late autumn, winter and early spring (such as from December 2019 to March 2020, from Asia to Europe to North America, etc.), or when the air conditioner is fully turned on in summer, it is about 29-23 degrees Celsius or lower (Asia to Europe). In the northern hemisphere such as North America, indoors such as workshops and shopping malls of family companies, cars, trams, subways, airplanes, etc.), the temperature of human respiratory tract drops to below 34 degrees Celsius, such as 32 degrees, 30 degrees, 28 degrees, and even 26 degrees. Isochronous or lower, the defense effect of leukocyte epithelial cells gradually declines until it disappears. Paralyzed, ineffective! The new coronavirus, bacteria, etc. are like entering an undefended respiratory tract, etc., such as entering an unmanned place, and driving straight in. In the paralyzed undefended human respiratory tract, nasopharynx, trachea, etc., it only takes a short 10 minutes for the new coronavirus to invade and invade defense cells such as these respiratory epithelial cells, and then after about 10 hours, each epithelial cell produces The first batch of about 1,000 viruses is released, and then the low temperature will continue to produce explosive virus production. After another 10 hours, the number of the second batch of viruses will be about 1,000 times 1,000, that is, 20 hours later, it will become 1 million. After another 10 hours, the number of the third batch of viruses will be about 1000 times 1000 times 1000, that is, 30 hours later, it will become 1 billion new coronaviruses, and more in the future! New Corona Virus Pneumonia Patient Appears! Therefore, in the case of high respiratory temperature of human beings, it is basically impossible to get new coronavirus pneumonia! Keeping warm is important! (22-4-5 11pm first draft, draft)
推荐阅读参考图书:
医学生理学,
人体生理学,
体温生理学,
生物物理学概论,
生物物理学:能量信息生命 等多种
Recommended reading reference books:
Medical Physiology,
human physiology,
body temperature physiology,
Introduction to Biophysics,
Biophysics: energy, information, life, etc.
推荐阅读文献:
Recommended reading literature:
冬天为啥容易感冒?事实没你想得那么简单
https://xw.qq.com/cmsid/20210113A026Z000?f=newdc
https://www.annualreviews.org/do ... ology-012420-022445
https://www.frontiersin.org/arti ... ed.2020.607786/full
PNAS:为何感冒容易在寒冷天气中发生?
https://news.bioon.com/article/6664455.html
https://www.pnas.org/doi/full/10.1073/pnas.1411030112
《自然》:为什么今年冬天新冠疫情看起来会恶化
https://www.cn-healthcare.com/ar ... ontent-1156929.html
Why COVID outbreaks look set to worsen this winter
https://www.nature.com/articles/d41586-020-02972-4
王辰院士:气温每上升1度可导致新冠肺炎发病率下降5.4%
https://www.sohu.com/a/433059861_359980
https://openres.ersjournals.com/ ... _campaign=shareline
Optimal temperature zone for the dispersal of COVID-19
传播 COVID-19 的最佳温度区
https://www.sciencedirect.com/sc ... i/S0048969720330047
Combinatorial influence of environmental temperature, obesity and cholesterol on SARS-CoV-2 infectivity
环境温度、肥胖和胆固醇对 SARS-CoV-2 感染性的综合影响
https://www.nature.com/articles/s41598-022-08485-6
Assessing the influence of climate on wintertime SARS-CoV-2 outbreaks
评估气候对冬季 SARS-CoV-2 爆发的影响
https://www.nature.com/articles/s41467-021-20991-1
A cross-sectional analysis of meteorological factors and SARS-CoV-2 transmission in 409 cities across 26 countries
26 个国家 409 个城市的气象因素和 SARS-CoV-2 传播的横断面分析
https://www.nature.com/articles/s41467-021-25914-8
The impact of weather on COVID-19 pandemic
天气对 COVID-19 大流行的影响
https://www.nature.com/articles/s41598-021-01189-3
Role of meteorological factors in the transmission of SARS-CoV-2 in the United States
气象因素在美国 SARS-CoV-2 传播中的作用
https://www.nature.com/articles/s41467-021-23866-7
Nature:Inner ear biomechanics reveals a Late Triassic origin for mammalian endothermy
https://www.nature.com/articles/s41586-022-04963-z
36.8℃,稳到不行的体温何时出现?《自然》:答案在2亿年前的耳朵里 恒温动物
https://www.linkresearcher.com/t ... TGm5aRtcS86fgSofmx0
https://paper.sciencenet.cn/html ... Mp3XS6nY7p_jHMqSqf4
Nature:A preoptic neuronal population controls fever and appetite during sickness
https://www.nature.com/articles/s41586-022-04793-z
为啥感染病毒常常会发热?《自然》研究揭示背后原因 下丘脑 提高生存率 求热
https://www.linkresearcher.com/t ... klAfUoc6o69rxMzKLKY
Cold exposure impairs extracellular vesicle swarm–mediated nasal antiviral immunity
https://www.sciencedirect.com/sc ... i/S0091674922014233
为什么新冠、流感都在冬天更流行?原来是鼻子里的免疫军团“冷到怠工”了!
https://news.bioon.com/article/d422e516955e.html
Nat Commun:体温升高会增加宿主身体对致病性病毒感染的抵抗力
https://news.bioon.com/article/a105e8468484.html
Nature communications: High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection
https://www.nature.com/articles/s41467-023-39569-0
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