在第二项新的研究中，来自美国基因泰克公司（Genentech）的研究人员解决了膀胱癌为何不会对免疫疗法作出反应。相关研究结果也于2018年2月14日在线发表在Nature期刊上，论文标题为“TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells”。论文通信作者为基因泰克公司的Sanjeev Mariathasan、Shannon J. Turley和Richard Bourgon。这些研究人员得出的结论与Batlle团队相同。
资讯出处：
Team paves the way to the use of immunotherapy to treat aggressive colon tumors
参考资料：
Daniele V. F. Tauriello, Sergio Palomo-Ponce, Diana Stork et al. TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis. Nature, Published online: 14 February 2018, doi:10.1038/nature25492 https://www.nature.com/articles/nature25492
Sanjeev Mariathasan, Shannon J. Turley, Dorothee Nickles et al. TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature, Published online: 14 February 2018, doi:10.1038/nature25501 https://www.nature.com/articles/nature25501
